Rob
TS Team
- Favourite Ride
- Steel Vengeance
Sad news, Captain Sir Tom Moore has passed away. What a final year of his life that he had though, and he'll always be remembered as a national hero.
-
ℹ️ Heads up...
This is a popular topic that is fast moving Guest - before posting, please ensure that you check out the first post in the topic for a quick reminder of guidelines, and importantly a summary of the known facts and information so far. Thanks.
Coronavirus
- Thread starter Jb85
- Start date
Thameslink Rail
TS Member
- Favourite Ride
- The Smiler
If you want some good news though, we have given out 10 million jabs!
https://www.bbc.co.uk/news/live/uk-...19824516968a03078677c9&pinned_post_type=share
https://www.bbc.co.uk/news/live/uk-...19824516968a03078677c9&pinned_post_type=share
Just watching bbc 6 o’clock news. Can’t see any link yet online but they were saying in breaking news that the vaccines are preventing spread of the virus, and the effectiveness of a a single shot vaccine is higher than expected and the study supports the 12 week delay between doses. Hopefully a link will appear soon on their website
Craig
TS Administrator
Matt N
TS Member
- Favourite Ride
- Mako (SeaWorld Orlando)
Excellent news! With the amount of AstraZeneca vaccines being used in the UK, as well as the comparative ease of administering them compared to Pfizer, 82.4% is still an excellent, excellent efficacy figure, and 67% efficacy at stopping transmission should really put a spanner in the works for the virus!
Rojo
TS Member
Thanks RoyJess. They are in regular contact with their GP and when I mentioned your suggestion, they said they ask every time but the surgery is only doing vaccines one day per week. Due to their oxygen needs they can't travel more than an hour, so they are pretty much stuck with only having it at the surgery. Fingers crossed it will be soon
I hope yourself and Jess are doing as well as you can and Jess is vaccinated soon!Some interesting news going on after a single dose of the Oxford-AstraZeneca vaccine prevents two-thirds of Covid transmissions and another study finds 99 per cent of participants retained antibodies for three months, while 88 per cent did so for six months.
Maybe, just maybe things could be looking up for Easter and beyond
They need to confirm the same approach works now for the Pfizer vaccine. I was reading on Twitter yesterday a feed from a care home manager who is still seeing high number of outbreaks in the home from people vaccinated with the vaccine, even past 21 days after having it.
Pfizer said it’s around 52% effective after one dose whereas an Israeli study said it was much lower than that at around 30-33%. Plus Pfizer are unsure what happens if you leave the vaccine second dose past 3 weeks. While the Oxford one is a conventional vaccine which may obey conventional rules, the mRNA vaccines are new and may not.
Pfizer said it’s around 52% effective after one dose whereas an Israeli study said it was much lower than that at around 30-33%. Plus Pfizer are unsure what happens if you leave the vaccine second dose past 3 weeks. While the Oxford one is a conventional vaccine which may obey conventional rules, the mRNA vaccines are new and may not.
Rob
TS Team
- Favourite Ride
- Steel Vengeance
I do worry that we are taking unnecessary risks with the 12 week gap for the Pfizer vaccine. The logic is sound for the Oxford vaccine but if the same does not apply to the Pfizer vaccine and it proves to be quite a bit less efficient with a gap of 12 weeks then we could end up being in a position whereby we have to start re-vaccinating the most vulnerable again in the spring/summer.
If the gamble does pay off and it works then great. But is it worth the risk? I guess we just have to trust those who have advised that this is the best policy for rollout.
If the gamble does pay off and it works then great. But is it worth the risk? I guess we just have to trust those who have advised that this is the best policy for rollout.
Dave
TS Founding Member
There are two different processing occurring between the mRNA and protein/ viral vector vaccines.
With traditional vaccines you have the antigen injected into the body (usually with a substance that angers the immune system), so you start the immune developing process from day 1.
mRNA vaccines inject RNA and then get the bodies cells to create the antigen, so you need time for that antigen to ramp up before then starting the immune response. So you likely will have a slower ramp up of immunity but you seem to ultimately get a stronger immune response.
I doubt the gap will have any major impact on the immune characteristics of delaying the mRNA vaccines as once you have the antigen the body is doing the same thing as the traditional vaccines. I still think they should have treated the mRNA vaccines with a little more caution in implementing a 12 week gap.
With traditional vaccines you have the antigen injected into the body (usually with a substance that angers the immune system), so you start the immune developing process from day 1.
mRNA vaccines inject RNA and then get the bodies cells to create the antigen, so you need time for that antigen to ramp up before then starting the immune response. So you likely will have a slower ramp up of immunity but you seem to ultimately get a stronger immune response.
I doubt the gap will have any major impact on the immune characteristics of delaying the mRNA vaccines as once you have the antigen the body is doing the same thing as the traditional vaccines. I still think they should have treated the mRNA vaccines with a little more caution in implementing a 12 week gap.
Interesting article here about the recent variants and why we are seeing them now.
https://www.vox.com/science-and-hea...-variants-uk-south-africa-brazil-b117-why-now
https://www.vox.com/science-and-hea...-variants-uk-south-africa-brazil-b117-why-now
Matt N
TS Member
- Favourite Ride
- Mako (SeaWorld Orlando)
On the subject of the Pfizer vaccine, it would appear that the government’s decision to delay the second dose could also be justified for Pfizer’s jab too, as a study conducted in Israel suggests that one dose is 90% effective after 3 weeks: https://apple.news/A1zBu-fcjTA6DdMrj6aBaiQ
Which is in complete contrast to another Israeli study which found it to be around 33% effective after one dose
https://www.bmj.com/content/372/bmj.n217
Dave
TS Founding Member
Israel is not a good test bed for the extension of vaccine interval as the only people not getting their 2nd vaccine after 21 days are people who for health reasons can’t. The numbers of delayed 2nd dose’s are so small you can’t make a conclusion in either direction.
The great laboratory called UK will be the first to demonstrate any problems/ successes with this strategy.....
Some good news and some bad news
Today I recived a surprised and unexpected phone call. All being well, I will be Jab this time next week. I personally would have like to see Jess have the jab before myself. Hopefully today's call is an indication that she might be called up sooner than later
Rojo
TS Member
Wow that's not the way around that should work but great news for you Roy. Hopefully Jess will be treated soon!
I has some news also, my Nain and Taid were called yesterday and vaccinated today
I was going to get them to ask if their GP was a member of Towerstreet! They have had AZ with no side effects and go back April 22nd for jab number 2.I has some news also, my Nain and Taid were called yesterday and vaccinated today
I'm so pleased for your Nain and Taid.
I think it's a case of age before beauty.
I'm still can't understand why they have called me in so soon. Unpaid carers are 6th on the list. I just hope there is no mix up and I get turned away on the day. I'm presuming it's because I a sole carer for someone who is vulnerable and have specialist care and is unable to get other carers in.
jon81uk
TS Member
I hope you don't mind me asking (say stop if we are too personal), but is it because you can go to the surgery more easily, but Jess is more vulnerable and needs a home visit from a nurse?
Tim
TS Member
- Favourite Ride
- Air / Blue Fire
It's worth asking why this is the case while you have the vaccine. It could be that there's a mistake in the system and while they have you as a registered carer Jess has somehow been missed off the vulnerable list. I imagine the list of carers is easier to track than the hundreds of disabilitys that are considered vulnerable.
Or as jon81uk said maybe it's just easier to vaccinate people that can travel ahead of those that can't. I know people in care homes are lagging behind for this reason as it's a longer process to vaccinate them.
Or as jon81uk said maybe it's just easier to vaccinate people that can travel ahead of those that can't. I know people in care homes are lagging behind for this reason as it's a longer process to vaccinate them.